Muscle weakness in patients with Becker disease is caused by unusual electrical activity in muscle fibres termed ‘plateau potentials’ that make them temporarily inactive, says a study published today in eLife.
An understanding of these mechanisms and the ion channels involved may help the search for more effective therapies for weakness in Becker disease and other muscle diseases, and help understand how electrical activity is regulated in muscles.
Recessive myotonia congenita, also known as Becker…
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